Vacancy Details: Head of Genomics Pipelines

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Earlham Institute

Earlham Institute is a vibrant, contemporary research institute and registered charity, working in an area of rapid technological development and innovation.

Earlham Institute is strategically funded by the BBSRC to lead the development of a skill base in bioinformatics and a genomics technology platform for UK bioscience. The Institute is located on the Norwich Research Park, together with its partners: the John Innes Centre, the Institute of Food Research, The Sainsbury Laboratory, the University of East Anglia and the Norfolk and Norwich University Hospital. The research park has an excellent reputation for research in plant and microbial sciences, interdisciplinary environmental science and food, diet and health, to which Earlham Institute contributes strengths in genomics and bioinformatics. Close links exist between the NRP partners and new opportunities for collaboration in exciting new initiatives are under development. The NRP recently received £26M of government investment to facilitate innovation and further develop infrastructure to attract science and technology companies to the Park to enhance the vibrant environment and realise economic impact from research investment.

Earlham Institute is a UK hub for innovative Bioinformatics through research, analysis and interpretation of multiple, complex data sets. It hosts one of the largest computing hardware facilities dedicated to life science research in Europe. This has been boosted recently by an e-Infrastructure grant to expand the data storage capacity to a multi-petabyte unit, deploying a high performance cluster and large-memory server enabling the allocation of processes requiring several terabytes of computing memory.

Earlham Institute’s state of the art DNA sequencing facility operates multiple complementary technologies for data generation that provide the foundation for analyses furthering our fundamental understanding of genomes and how they function. We aim to be at the forefront of technological advances and are developing and implementing technologies to generate and analyse new types of data. We also develop novel platforms to provide access to computational tools and processing capacity for multiple academic and industrial users and promoting applications of computational bioscience. Earlham Institute has one fully owned subsidiary, Genome Enterprise Ltd (GEL) via which it offers genomic and bioinformatics services on a trading basis and works with commercial providers on a partnership basis. Earlham Institute also receives specific funding to enable knowledge exchange programmes which are supported across the institute teams.

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Post Number1003288
Job TitleHead of Genomics Pipelines
Closing Date9 Aug 2017
GradeSC4
Starting Salary£48,000 - £58,500
Hours per week 37
Expected/Ideal Start Date 01 Sep 2017
Months Duration Indefinite
Main purpose of the job The Genomics Pipelines Group at the Earlham Institute (EI) will be responsible for the high throughput pipeline part of EI’s national capability in genomics and single cell (NCGSC). The NCGSG delivers next generation sequence data on a range of technology platforms and maintains state of the art methodology.

The workflow will be planned in an environment of changing technologies and procedures and there will be a requirement to experiment with processes at the same time as delivering high quality data for multiple projects.

As well as delivering sequencing data to EI’s own research groups, the Group will deliver the NCGSC to stakeholders of our strategic partners, Biotechnology and Biological Science Research Council (BBSRC) and operational services to other international researcher, academics, and EI’s Trading subsidiary Genome Enterprise Limited.

The Head of Genomics Pipelines will be a member of the Senior Management Team, leading and managing a team of ~15, consisting of three teams: Project Management, Sequencing Pipelines and Automation. The Group will work closely with the Core Bioinformatics Group. The post holder will be responsible for ensuring that the Genomics Pipeline Group remain flexible, pushes the boundaries of current technology and delivers top quality output. They will be responsible for fulfilling EI’s vision to build excellence in genomics and computational bioscience and ensure that the pipeline.
Advert Text Applications are invited for an enthusiastic, motivated and exceptional individual to join the Earlham Institute (EI) as Head of Genomics Pipelines.

The role:
The Head of Genomics Pipelines will be a member of the Senior Management Team, leading and managing a team of ~15, consisting of three teams: Project Management, Sequencing Pipelines and Automation. The Group will work closely with the Core Bioinformatics Group. The post holder will be responsible for ensuring that the Genomics Pipeline Group remain flexible, pushes the boundaries of current technology and delivers top quality output. They will be responsible for fulfilling EI’s vision to build excellence in genomics and computational bioscience.

The Genomics Pipelines Group at the Earlham Institute (EI) will be responsible for the high throughput pipeline part of EI’s national capability in genomics and single cell (NCGSC). The NCGSC delivers next generation sequence data on a range of technology platforms and maintains state of the art methodology.

Required qualifications and experience:
The ideal candidate will possess a PhD in a science subject, or have substantial equivalent experience. They will have an in-depth knowledge of molecular biology and/or biochemistry related to genome biology. A demonstrable ability to deliver projects within time and budget constraints is essential The post holder will be experienced in managing teams and have excellent communication skills.
Key relationships Internal: EI’s Director, Director of Operations and Science and Senior Management Team.
Genomics Pipelines Group – All members from Project Management, Sequencing Pipelines, and Core Bioinformatics Team. EI’s Science Faculty and Research Teams. EI Board of Trustee Directors. EI’s Business Analyst.

External: VIP Visitors, including MPs, and other senior decision makers. Senior visitors to EI, collaborators, potential employees, Health and Safety Representatives, platform suppliers, conference attendees, Advanced Training visitors and Outreach contacts.
Main Activities & ResponsibilitiesPercentage
Deliver a world leading National Capability in Genomics and Single Cell, meeting or exceeding the Key Performance Indicators (KPIs). With the aim of constantly improving the delivery and offering to its key stakeholders and customers.25
Direct and lead the Genomics Pipelines Group, setting and communicating its vision and objectives. Manage 15 people, within three teams: Project Management, Sequencing Pipeline team and Automation. 20
Review processes, and ensure that the Group uses efficient and effective processes and system. That it meets all H&S requirements, complies with regulations, and follows good practices.20
Lead and oversee proactive research into new technologies or protocols and their implementation.10
Establish good communication with stakeholders, reviewing customer feedback and adjusting processes accordingly.10
Manage the group budgets, ensure that the charging model is robust, current and reflective of cost base. Working with EI’s Business Analyst. Ensure efficient stock levels and systems are robust and follow good practice.5
Member of EI’s Senior Management Team. Contribute towards wider issues outside the Genomics Pipelines Group such as wider operational issues, business planning etc. Represent EI at Norwich Research Park committees. 5
As agreed with line manager, any other duties commensurate with the role.5

Education & QualificationsRequirementImportance
PhD in a scientific subject, or equivalent experienceEssential
Bachelors degree in a scientific subject, or equivalent experienceEssential
Project Management PRINCE II qualificationDesirable
MBA or similar business focussed qualificationDesirable

Specialist Knowledge & SkillsRequirementImportance
In depth knowledge of managing the issues of a team working in high throughput DNA sequencingEssential
Demonstrated ability to deliver projects within time and budget constraintsEssential
Demonstrable skills of managing teams undergoing significant changeEssential
Demonstrated ability to develop team members through training, delegated responsibility and skills improvementEssential
Good knowledge of molecular biology/biochemistry relevant to genome biologyEssential
Good awareness of sequence data analysis methodsEssential
NEBOSH certificate and understanding of Health and Safety in a lab environmentDesirable
Computational knowledge, including: UNIX, bioinformatics programmes for sequence assembly/specialist knowledge of molecular biology related to sequence generationDesirable
Highly experienced in the operation of multiple sequencing platformsDesirable
Ability to effectively deliver training to othersDesirable

Relevant ExperienceRequirementImportance
Significant experience of delivering to a high standard a service with a customer focus, within a culture that sets Essential
Evidence of enabling world class research outcomesEssential
Experience of working as part of a senior management teamEssential
Experience of working in a commercially focused organisation or pipelineDesirable
Good publication record or proven track record in scientific writing, both papers and grants, successfully securing funding (UK, EU or international)Desirable

Management and LeadershipRequirementImportance
Demonstrated experience of managing a large multi-disciplinary complex science operational team (over 15)Essential

Interpersonal & Communication SkillsRequirementImportance
Strong problem solving skillsEssential
Excellent organisational and team management skillsEssential
Able to communicate, influence and work cooperatively with scientists from a range of disciplines and at different levels of seniorityEssential
Excellent communication and diplomacy skillsEssential

Additional RequirementsRequirementImportance
Must be able to travel and work a non-conventional work pattern at timesEssential
Promotes equality and values diversityEssential
Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to workEssential
Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the InstituteEssential
Ability to maintain confidentiality and security of information where appropriateEssential