Vacancy Details: Postdoctoral Scientist - Microbial Genomics

To apply for this job

  • Either
    • Download, Save and Complete a copy of the application form using Microsoft Word
    Or
    • Prepare a copy of your CV that contains all the information requested in the application form
  • Submit your application document (single file in word or acrobat format) together with your Personal details, Referees and Equal Opportunities Monitoring data

Earlham Institute

Earlham Institute is a vibrant, contemporary research institute and registered charity, working in an area of rapid technological development and innovation.

Earlham Institute is strategically funded by the BBSRC to lead the development of a skill base in bioinformatics and a genomics technology platform for UK bioscience. The Institute is located on the Norwich Research Park, together with its partners: the John Innes Centre, the Institute of Food Research, The Sainsbury Laboratory, the University of East Anglia and the Norfolk and Norwich University Hospital. The research park has an excellent reputation for research in plant and microbial sciences, interdisciplinary environmental science and food, diet and health, to which Earlham Institute contributes strengths in genomics and bioinformatics. Close links exist between the NRP partners and new opportunities for collaboration in exciting new initiatives are under development. The NRP recently received £26M of government investment to facilitate innovation and further develop infrastructure to attract science and technology companies to the Park to enhance the vibrant environment and realise economic impact from research investment.

Earlham Institute is a UK hub for innovative Bioinformatics through research, analysis and interpretation of multiple, complex data sets. It hosts one of the largest computing hardware facilities dedicated to life science research in Europe. This has been boosted recently by an e-Infrastructure grant to expand the data storage capacity to a multi-petabyte unit, deploying a high performance cluster and large-memory server enabling the allocation of processes requiring several terabytes of computing memory.

Earlham Institute’s state of the art DNA sequencing facility operates multiple complementary technologies for data generation that provide the foundation for analyses furthering our fundamental understanding of genomes and how they function. We aim to be at the forefront of technological advances and are developing and implementing technologies to generate and analyse new types of data. We also develop novel platforms to provide access to computational tools and processing capacity for multiple academic and industrial users and promoting applications of computational bioscience. Earlham Institute has one fully owned subsidiary, Genome Enterprise Ltd (GEL) via which it offers genomic and bioinformatics services on a trading basis and works with commercial providers on a partnership basis. Earlham Institute also receives specific funding to enable knowledge exchange programmes which are supported across the institute teams.

disability confident employer

Advancing gender equality in science, engineering and technology.

Post Number1003304
Job TitlePostdoctoral Scientist - Microbial Genomics
Closing Date7 Sep 2017
GradeSC6
Starting Salary£30,750 - £37,750
Hours per week 37
Months Duration 36
Main purpose of the job The Earlham Institute (EI, Norwich, UK) is looking for a highly motivated individual to join the Hall laboratory to lead the analysis of microbial genomics and metagenomics datasets. We are looking for a highly motivated and creative individual with good bioinformatics knowledge and an interest in microbiology. The post-holder will work alongside members of the group to analyse genomic and transcriptomic datasets generated at EI to identify genetic changes leading to important phenotypes. The projects delivered by this post will include development of methods for improved metagenomics analysis and single cell analysis from microbial communities, investigating the species and strain diversity of foodborne pathogens and investigating the genetic changes associated with virulence and antimicrobial resistance.
Department Organisms and Ecosystems
Advert Text Postdoctoral Scientist – Microbial Genomics


Applications are invited for a highly motivated Postdoctoral Scientist to join the Laboratory of Neil Hall in the Organisms and Ecosystems Group at the Earlham Institute.


Background:


The Hall group uses comparative and functional genomics, and population genetics approaches to understand pathogen evolutions and identify the genes involved in host interaction. The Hall laboratory also studies microbial communities associated with humans and other animals.


The role:


The post-holder will work alongside members of the Group to analyse genomic and transcriptomic datasets generated at EI to identify genetic changes leading to important phenotypes. The projects delivered by this post will include development of methods for improved metagenomics analysis and single cell analysis from microbial communities, investigating the species and strain diversity of foodborne pathogens and investigating the genetic changes associated with virulence and antimicrobial resistance.


The post will also work closely with the Korcsmaros group to apply network modelling to genomic data. The role will also involve working alongside other bioinformaticians, computer scientists and molecular biologists within the internal science faculty as well as external collaborators.


The ideal candidate:


We are looking for a highly motivated and creative individual with good bioinformatics knowledge and an interest in microbiology. The ideal candidate will hold a PhD in biological science, computer science or another relevant field. They will also possess demonstrable experience of writing scientific papers.


Additional information:


Salary on appointment will be within the range £30,750 to £37,750 per annum depending on qualifications and experience. This post is for a contract of three years.


For further information and details of how to apply, please visit our web site http://jobs.earlham.ac.uk/ or contact Human Resources, Norwich BioScience Institutes Partnership, Norwich Research Park, Colney, Norwich, NR4 7UH, UK, 01603 450462 quoting reference 1003304.


As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.


The closing date for applications will be Wednesday 6th September 2017
Key relationships The post will also work closely with the Korcsmaros group to apply network modelling to genomic data. The role will also involve working alongside other bioinformaticians, computer scientists and molecular biologists within the internal science faculty as well as external collaborators.
Main Activities & ResponsibilitiesPercentage
1. Working with group leaders to design and implement experiments 2. Analysis of large complex microbial genomic and transcriptomic datasets 3. Working with collaborators providing clinical and environmental samples 4. Working alongside our project management and laboratory teams to ensure data is processed according to project requirements 5. Writing papers and presentations at conferences to communicate results 6. Contributing to grant proposals from the group 7. Helping and advising PhD students and visiting scientists 8. Contributing to training events hosted by EI 9. As agreed with the line manager, any other duties commensurate with the nature of the role 100

Education & QualificationsRequirementImportance
Hold a PhD in biological science, computer science or another relevant subject area.Essential

Specialist Knowledge & SkillsRequirementImportance
Have a good understanding of the Next Generation Sequencing Technologies.Essential
Have a high level of skill and experience of scripting, and analysis of large datasetsEssential
Microbiology techniques and working with foodborne pathogens Desirable
Transcriptomics analysis upon bacterial infection Desirable
Basic molecular biology techniques, qPCR, Western blot, cloning, gene mutagenesis Desirable
Metagenomics or single cell analysis experience Desirable

Relevant ExperienceRequirementImportance
Have demonstrated experience of writing scientific papers. Essential

Interpersonal & Communication SkillsRequirementImportance
Demonstrated ability to work independently, using initiative and applying problem solving skillsEssential
Attention to detailEssential
Good organisational skills and able to multi-task effectivelyEssential
High degree of commitment and motivationEssential
Excellent team working and communication skillsEssential

Additional RequirementsRequirementImportance
Promotes equality and values diversityEssential
Ability to maintain confidentiality and security of information where appropriateEssential
Able to present a positive image of self and the Institute, promoting both the international reputation and public engagement aims of the InstituteEssential
Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring it is a great place to workEssential